Deddi Prima Putra. Disampaikan pada Semnas dan Muswil ISMAFARSI Sumatera II Fakultas Farmasi Unand- 23 April 2016 PADANG

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1 Deddi Prima Putra Disampaikan pada Semnas dan Muswil ISMAFARSI Sumatera II Fakultas Farmasi Unand- 23 April 2016 PADANG

2 Penduduk Indonesia 2035* 2030* 2025* 2020* 2015* Sumber : diolah dr BPS 2015 *) Perkiraan

3 Persentase Penduduk yang Mengobati Sendiri Selama Sebulan Terakhir (%) Ind (rerata) Sumbar Sumber : diolah dr BPS 2015

4 Persentase penduduk yang mengalami keluhan kesehatan sebulan yang lalu Sumber : diolah dr BPS 2015

5 Persentase Penduduk yang Menggunakan Obat Tradisional ( ) Sumber : diolah dr BPS 2015

6 Definisi Herbal Medicine Herbal Medicine merupakan bahan yang digunakan untuk Pengobatan Tradisional (Traditional Medicine) WHO mendefinisikan Traditional Medicine : It is the sum total of the knowledge, skills and practices based on the theories, beliefs and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health, as well as in the prevention, diagnosis, improvement or treatment of physical and mental illnesses Other terms; complementary/alternative/non-conventional medicine

7 Traditional use of herbal medicines Herbal medicines include herbs, herbal materials, herbal preparations and finished herbal products, that contain as active ingredients parts of plants, or other plant materials, or combinations. Category Herbal Medicine by WHO; Category 1: Indigenous herbal medicines Category 2: Herbal medicines in systems Category 3: Modified herbal medicines Category 4: Imported products with a herbal medicine base

8 Why Herbal Medicine? Jutaan penduduk di negara berkembang selalu menggunakan Herbal Medicine karena mereka percaya dan terlebih kerena merupakan their system of medicine Mudah diperoleh, ketersediaan setiap waktu para Healer/ Dukun, keyakinan akan bahan alam (natural thing) khususnya dipedesaan. Harga yang murah dan terjangkau

9 Amankah Herbal Medicine? There is a widespread misconception that natural always means safe, and A common belief that remedies from natural origin are harmless and carry no risk. However, some medicinal plants are inherently toxic.

10 WHO established a minimum requirements for assessment of safety of herbal medicines: Category 1: safety established by use over long time Category 2: safe under specific conditions of use (such herbal medicines should preferably be covered by wellestablished documentation) Category 3: herbal medicines of uncertain safety (the safety data required for this class of drugs will be identical to that of any new substance)

11 Usaha untuk Meningkatkan Safety dan Efficacy Penggunaan Herbal Koordinasi dan Harmonisasi masing-masing negara dalam menghasilkan regulasi ttg Herbal Medicine. Quality Assurance produk herbal seperti ; Implementasi Good Agricultural and Collection Practice (GACP), Good Manufacturing Practice (GMP), dll. Farmacovigilance dan Pengawasan iklan. Penyusunan Monografi dan Farmakope Herbal.

12 Herbal Medicine di Indonesia Perka BPOM RI No HK

13 Potensi Herbal Indonesia 1. Indonesia merupakan mega-center keanekaragaman hayati dunia (2 nd in the world) 2. Memiliki species tumbuhan dan sekitar diantaranya tumbuhan berkhasiat spesies telah digunakan sebagai bahan obat tradisional (OT) oleh industri OT.

14 GLOBAL SCENARIO GLOBAL HERBAL MARKET INCL NUTRACEUTICALS $ 70.4 BILLION EXCLUSIVE GLOBAL HERBAL MARKET $ 24.2 BILLION 49% 31% 70% 33% 49% 42% 10% US $ Billion Global Sales of Herbal Medicine Year Year Year Year 2002 From CK Katiyar, 2006

15 Strategi Pengembangan Herbal Indonesia From Dir. Bina Prod dan Distribusi Kefarmasian

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17 From Dir. Bina Prod dan Distribusi Kefarmasian

18 Jenis Tumbuhan Obat yang Banyak Digunakan From Gunawan, 2014

19 Industri Obat Tradisional di Indonesia Form, Sido Muncul report, 2014

20 Form, Sido Muncul report, 2014

21 Jumlah Produk Teregistrasi pada BPOM Form, Sido Muncul report, 2014

22 Potensi dan Pemanfaatan Tanaman Lokal dalam Herbal Medicine Pegagan = Centella asiatica

23 Etnobotanical Time-line Tahun Perkembangan Kegunaan 3000 yl Indian Ayurvedic Asma, bronchitis, dropsi, elepantiasis, lepra, ganggian ginjal, leucorhoea, gangguan kulit, uretritis 2000 yl Chinese Shennong Herbal Leucorrhoe, fever 1884 French Pharmacopoeia 1983 British Herbal Pharmacopoeia Kegunaan topikal: Ulser, wounds, sikatris stlh operasi

24 Produk Development Time-line Tahun Nama Produk Negara 1968 TECA (Like Madecassol), Oitment 1% Portugal 1969 Madecassol, Krim 1%, tablet Belgia 1973 TECA, tablet Portugal 1974 TECA (Madecassol), Tablet Perancis 1975 TECA, Cream 1%, Powder 2% Perancis 1976 TECA, steril Perancis 1982 TECA (Centellase), Tablet Italy 1997 Bilim (like Madecassol), Oitment 1% Greece

25 Kandungan Senyawa Aktif pada Pegagan

26 Elephantopus scaber L. (Tapak Liman)

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28 Kegunaan Tradisional Kabeer and Prathapan, 2014

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30 Kajian Bioaktivitas dan Farmakologi

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32 Produk/ Sediaan Elephantopus scaber L.

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34 Pengembangan Tumbuhan Obat di Industri From; Trade in Medicinal Plant, FAO-Rome, 2004

35 Added Value Phytomedicine Uncaria gambier Robx Marker Nano/Mikro katekin 220 USD/ 25 mg??? Ekstrak Terpurifikasi Rp rb/ Kg Ekstrak gambir Rp30-45 rb/kg Daun Gambir Rp 800/kg

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