Lampiran 1 DAFTAR RIWAYAT HIDUP Nama : Mira Tania Andriana NIM : 120100413 Tempat, Tanggal Lahir : Medan, 15 Juni 1994 Agama : Islam Alamat : Jl. Karya Wisata Komplek Johor Indah Permai I Blok VI no.31 Medan Jenis Kelamin : Perempuan Alamat Email : miraasyifa@gmail.com Riwayat Pendidikan : 1. TK Alfitriah 1999 2000 2. SDIT Alfitriah 2000 2006 3. SMP HARAPAN 3 2006 2009 4. SMA HARAPAN 3 2009 2012 5. Fakultas Kedokteran 2012 sekarang Riwayat Organisasi : 1. Anggota Departeman Wirausaha PEMA FK USU 2012 2013 2. Sekretaris Divisi Pendidikan dan Pelatihan SCOPH PEMA FK USU 2013-2014 3. Anggota Divisi HBI-PM BKM Ar-Rahmah 2015-sekarang
Lampiran 1
LAMPIRAN 4 KELOMPOK HBV Rekam Jenis Trombosit (10 3 /mm) No Medis kelamin Usia AST ALT ALP GTP ALBUMIN PT HB T.Marker 1 61.82.90 pria 32 157 68 331 404 2,1 1,9 7,1 81 >1210.00 2 59.46.18 pria 39 425 52 1329 420 2,8 1,18 12,6 99 >1210.00 3 59.48.20 pria 30 81 26 92 99 1,8 1 6,3 102 >1210.00 4 60.10.42 pria 53 364 58 125 546 2,8 1,92 9,6 161 >1210.00 5 60.74.44 pria 45 86 36 130 322 32,2 0,95 16 325 1210.00 6 62.47.20 wanita 30 241 46 315 463 3,1 1,17 7,9 288 >1210.00 7 59.26.43 wanita 31 209 47 478 247 1,8 1,28 10 355 16,8 8 58.80.88 pria 33 42 134 238 70 2,4 1,13 15,6 339 15 9 58.84.39 wanita 48 1075 106 334 527 2,9 1,37 7,4 537 20 10 59.37.61 wanita 41 61 38 91 55 1,5 1,2 8,1 23 25,68 11 59.55.58 pria 30 421 38 182 130 2,8 1,41 4,5 425 >1210.00 12 60.01.25 pria 39 289 60 174 250 3 1,17 13,4 227 1210 13 61.11.18 wanita 46 47 24 127 150 2,1 1,2 9,7 232 1210 14 61.15.46 pria 59 184 54 194 161 2,2 1,21 9 70 >1210 15 61.22.47 pria 50 312 66 529 584 2,5 1,1 10,1 321 >1210 16 61.76.77 pria 36 312 66 529 584 2,5 1,1 9 244 >1210.00 17 60.25.57 pria 38 284 105 166 190 3,4 1,18 16,2 204 >1210.00 18 61.49.18 pria 49 44 27 92 60 3,7 0,3 15,8 178 33,78
LAMPIRAN 4 KELOMPOK HCV No Rekam Medis Jk Usia AST ALT ALP GTP ALBUMIN PT HB Trombosit (10 3 /mm) T.Marker 1 61.53.11 pria 37 81 50 166 297 2,8 1,21 19,2 313 1210.00 2 61.78.38 pria 42 71 53 66 21 2,2 1,17 8,6 107 1210.00 3 61.62.18 wanita 52 53 37 70 20 2 0,8 9,1 83 1210.00 4 58.78.03 pria 76 140 60 170 270 2,9 1,5 9,4 270 1210 5 54.46.33 pria 75 130 39 95 132 3,2 1,32 13,2 260 >1210.00 6 56.53.17 pria 70 160 81 110 149 2,3 1,2 2,59 153 12,76 7 57.61.69 pria 42 80 31 129 82 2,6 1,34 13,7 155 34 8 61.53.11 pria 37 109 60 170 280 3 1,12 15,6 217 20,6
LAMPIRAN 4 RADIOLOGI KELOMPOK HBV NO Rekam Medis USG CT-SCAN multinoduler di lobus 1 61.82.90 kanan 2 59.46.18 nodul(+)di lobus kanan 3 59.48.20 multinoduler di lobus kanan dan kiri 4 60.10.42 5 60.74.44 multinoduler di lobus kanan dan kiri 6 62.47.20 multinoduler di lobus kanan dan kiri 7 59.26.43 multinoduler di lobus kanan dan kiri 8 58.80.88 9 58.84.39 multinoduler di lobus kanan 10 59.37.61 noduler di lobus kanan 11 59.55.58 Reguler 12 60.01.25 multinoduler di lobus kanan dan kiri 13 61.11.18 noduler di lobus kanan 14 61.15.46 multinoduler di lobus kanan dan kiri 15 61.22.47 multinoduler di lobus kanan 16 61.76.77 multinoduler di lobus kanan 17 60.25.57 noduler di lobus kanan 18 61.49.18 noduler di lobus kanan noduler di lobus kanan noduler di lobus kanan
LAMPIRAN 4 RADIOLOGI KELOMPOK HCV No USG CT-SCAN 1 61.53.11 noduler di lobus kanan 2 61.78.38 multinoduler di lobus kanan 3 61.62.18 multinoduler di lobus kanan 4 58.78.03 noduler di lobus kanan 5 54.46.33 noduler di lobus kanan 6 56.53.17 noduler di lobus kanan 7 57.61.69 multinoduler di lobus kanan dan kiri 8 61.53.11 multinoduler di lobus kanan dan kiri
Valid Kelompok Pasien hepatoma berdasarkan etiologi Frequency Percent Valid Percent Cumulative Percent HBV 18 69,2 69,2 69,2 HCV 8 30,8 30,8 100,0 Total 26 100,0 100,0 Kelompok Pasien hepatoma * Jenis Kelamin Crosstabulation Jenis Kelamin Total Pria Wanita Count 13 5 18 HBV % within Kelompok Pasien 72,2% 27,8% 100,0% Kelompok Pasien hepatoma hepatoma Count 7 1 8 HCV % within Kelompok Pasien hepatoma 87,5% 12,5% 100,0% Count 20 6 26 Total % within Kelompok Pasien hepatoma 76,9% 23,1% 100,0% Kelompok Pasien hepatoma * Kelompok Usia Responden Crosstabulation Kelompok Pasien hepatoma Total HBV HCV Kelompok Usia Responden Total < = 40 41-50 51-60 61-70 > 70 Tahun Tahun Tahun tahun Tahun Count 10 6 2 0 0 18 % within Kelompok Pasien hepatoma 55,6% 33,3% 11,1% 0,0% 0,0% 100,0% Count 2 2 1 1 2 8 % within 25,0% 25,0% 12,5% 12,5% 25,0% 100,0% Kelompok Pasien hepatoma Count 12 8 3 1 2 26 % within Kelompok Pasien hepatoma 46,2% 30,8% 11,5% 3,8% 7,7% 100,0%
Nilai Laboratorium Kelompok HBV Statistic Std. Error 40,50 2,099 95% Confidence Interval for Lower Upper 36,07 44,93 5% Trimmed 40,06 Median 39,00 Usia Variance 79,324 Std. Deviation 8,906 Minimum 30 Maximum 59 Range 29 Interquartile Range 17 Skewness,464,536 kadar ast kadar alt Kurtosis -,777 1,038 257,44 57,043 Lower 137,09 95% Confidence Interval for Upper 377,80 5% Trimmed 223,99 Median 225,00 Variance 58571,085 Std. Deviation 242,015 Minimum 42 Maximum 1075 Range 1033 Interquartile Range 249 Skewness 2,374,536 Kurtosis 7,580 1,038 58,39 7,062 Lower 43,49 95% Confidence Interval for Upper 73,29
kadar alp kadar gtp 5% Trimmed 56,10 Median 53,00 Variance 897,663 Std. Deviation 29,961 Minimum 24 Maximum 134 Range 110 Interquartile Range 29 Skewness 1,244,536 Kurtosis 1,242 1,038 303,11 69,547 Lower 156,38 95% Confidence Interval for Upper 449,84 5% Trimmed 257,90 Median 188,00 Variance 87063,163 Std. Deviation 295,065 Minimum 91 Maximum 1329 Range 1238 Interquartile Range 244 Skewness 2,719,536 Kurtosis 8,814 1,038 292,33 45,144 Lower 197,09 95% Confidence Interval for Upper 387,58 5% Trimmed 289,31 Median 248,50 Variance 36683,765 Std. Deviation 191,530 Minimum 55 Maximum 584 Range 529 Interquartile Range 357 Skewness,307,536 Kurtosis -1,472 1,038
kadar albumin kadar pt kadar Hb 4,200 1,6526 Lower,713 95% Confidence Interval for Upper 7,687 5% Trimmed 2,794 Median 2,650 Variance 49,162 Std. Deviation 7,0116 Minimum 1,5 Maximum 32,2 Range 30,7 Interquartile Range,9 Skewness 4,194,536 Kurtosis 17,712 1,038 1,2094,08137 Lower 1,0378 95% Confidence Interval for Upper 1,3811 5% Trimmed 1,2205 Median 1,1800 Variance,119 Std. Deviation,34524 Minimum,30 Maximum 1,92 Range 1,62 Interquartile Range,20 Skewness -,131,536 Kurtosis 3,323 1,038 10,461,8543 Lower 8,659 95% Confidence Interval for Upper 12,264 5% Trimmed 10,473 Median 9,650 Variance 13,137 Std. Deviation 3,6244 Minimum 4,5
Maximum 16,2 Range 11,7 Interquartile Range 6,2 Skewness,409,536 Kurtosis -,944 1,038 233,94 31,968 95% Confidence Interval for Lower Upper 166,50 301,39 5% Trimmed 228,83 Median 229,50 kadar trombosit Variance 18394,997 Std. Deviation 135,628 Minimum 23 Maximum 537 Range 514 Interquartile Range 227 Skewness,440,536 Kurtosis -,104 1,038 Tests of Normality kelompok HBV Kolmogorov-Smirnov a Shapiro-Wilk Statistic df Sig. Statistic df Sig. Usia,133 18,200 *,929 18,189 kadar ast,189 18,089,753 18,000 kadar alt,208 18,039,877 18,023 kadar alp,236 18,009,679 18,000 kadar gtp,148 18,200 *,900 18,058 kadar albumin,473 18,000,326 18,000 kadar pt,222 18,020,837 18,005 kadar Hb,206 18,041,917 18,113 kadar trombosit,112 18,200 *,971 18,815 *. This is a lower bound of the true significance. a. Lilliefors Significance Correction
Usia kadar ast kadar alt kadar alp Nilai Laboratorium kelompok HCV Statistic Std. Error 53,88 6,052 95% Confidence Interval for Lower 39,57 Upper 68,18 5% Trimmed 53,58 Median 47,00 Variance 292,982 Std. Deviation 17,117 Minimum 37 Maximum 76 Range 39 Interquartile Range 36 Skewness,436,752 Kurtosis -2,071 1,481 103,00 13,310 95% Confidence Interval for Lower 71,53 Upper 134,47 5% Trimmed 102,61 Median 95,00 Variance 1417,143 Std. Deviation 37,645 Minimum 53 Maximum 160 Range 107 Interquartile Range 64 Skewness,268,752 Kurtosis -1,353 1,481 51,38 5,679 95% Confidence Interval for Lower 37,95 Upper 64,80 5% Trimmed 50,86 Median 51,50 Variance 257,982 Std. Deviation 16,062 Minimum 31 Maximum 81 Range 50 Interquartile Range 23 Skewness,642,752 Kurtosis,354 1,481 122,00 15,415 95% Confidence Interval for Lower 85,55 Upper 158,45 5% Trimmed 122,44 Median 119,50 Variance 1900,857 Std. Deviation 43,599 Minimum 66 Maximum 170 Range 104 Interquartile Range 93 Skewness -,071,752
kadar gtp kadar albumin kadar pt kadar Hb kadar trombosit Kurtosis -1,857 1,481 156,38 40,328 95% Confidence Interval for Lower 61,02 Upper 251,73 5% Trimmed 156,14 Median 140,50 Variance 13010,554 Std. Deviation 114,064 Minimum 20 Maximum 297 Range 277 Interquartile Range 241 Skewness,089,752 Kurtosis -1,854 1,481 2,625,1497 95% Confidence Interval for Lower 2,271 Upper 2,979 5% Trimmed 2,628 Median 2,700 Variance,179 Std. Deviation,4234 Minimum 2,0 Maximum 3,2 Range 1,2 Interquartile Range,8 Skewness -,216,752 Kurtosis -1,357 1,481 1,2075,07208 95% Confidence Interval for Lower 1,0371 Upper 1,3779 5% Trimmed 1,2139 Median 1,2050 Variance,042 Std. Deviation,20387 Minimum,80 Maximum 1,50 Range,70 Interquartile Range,20 Skewness -,890,752 Kurtosis 2,130 1,481 11,424 1,8015 95% Confidence Interval for Lower 7,164 Upper 15,684 5% Trimmed 11,483 Median 11,300 Variance 25,965 Std. Deviation 5,0955 Minimum 2,6 Maximum 19,2 Range 16,6 Interquartile Range 6,4 Skewness -,248,752 Kurtosis,286 1,481 194,75 29,249 95% Confidence Interval for Lower 125,59
Upper 263,91 5% Trimmed 194,39 Median 186,00 Variance 6844,214 Std. Deviation 82,730 Minimum 83 Maximum 313 Range 230 Interquartile Range 149 Skewness,054,752 Kurtosis -1,484 1,481 Tests of Normality kelompok HCV Kolmogorov-Smirnov a Shapiro-Wilk Statistic df Sig. Statistic df Sig. Usia,256 8,131,823 8,050 kadar ast,221 8,200 *,947 8,677 kadar alt,171 8,200 *,948 8,691 kadar alp,219 8,200 *,878 8,179 kadar gtp,215 8,200 *,882 8,196 kadar albumin,160 8,200 *,956 8,774 kadar pt,209 8,200 *,929 8,509 kadar Hb,165 8,200 *,971 8,905 kadar trombosit,185 8,200 *,947 8,677 *. This is a lower bound of the true significance. a. Lilliefors Significance Correction Kelompok Pasien hepatoma * Bentuktumor_USG Crosstabulation Kelompok Pasien hepatoma Total HBV HCV Radiologi_USG Total Reguler Nodul Multinodular Count 1 5 9 15 % within Kelompok Pasien hepatoma 6,7% 33,3% 60,0% 100,0% Count 0 2 4 6 % within Kelompok Pasien hepatoma 0,0% 33,3% 66,7% 100,0% Count 1 7 13 21 % within Kelompok Pasien hepatoma 4,8% 33,3% 61,9% 100,0%
Kelompok Pasien hepatoma Total HBV HCV Kelompok Pasien hepatoma * Lokasi_USG Crosstabulation Lokasi_USG Total Tidak Ada Lobus Kanan Lobus Kanan dan Kiri Count 1 8 6 15 % within Kelompok Pasien 6,7% 53,3% 40,0% 100,0% hepatoma Count 0 4 2 6 % within Kelompok Pasien 0,0% 66,7% 33,3% 100,0% hepatoma Count 1 12 8 21 % within Kelompok Pasien hepatoma 4,8% 57,1% 38,1% 100,0% Kelompok Pasien hepatoma Total Kelompok Pasien hepatoma * Bentuktumor_CT Crosstabulation HBV HCV Radiologi_CT Total Nodul Multinodular Count 2 1 3 % within Kelompok Pasien hepatoma 66,7% 33,3% 100,0% Count 2 0 2 % within Kelompok Pasien hepatoma 100,0% 0,0% 100,0% Count 4 1 5 % within Kelompok Pasien hepatoma 80,0% 20,0% 100,0% Kelompok Pasien hepatoma * Lokasi_CT Crosstabulation Lokasi_CT Total Lobus Kanan Count 3 3 HBV % within Kelompok Pasien hepatoma 100,0% 100,0% Kelompok Pasien hepatoma Count 2 2 HCV % within Kelompok Pasien hepatoma 100,0% 100,0% Count 5 5 Total % within Kelompok Pasien hepatoma 100,0% 100,0%
kadar tumor marker Gambaran Tumor Marker HBV Statistic Std. Error 880,07 129,031 Lower 607,84 95% Confidence Interval for Upper 1152,30 5% Trimmed 909,80 Median 1210,00 Variance 299681,77 1 Std. Deviation 547,432 Minimum 15 Maximum 1210 Range 1195 Interquartile Range 1178 Skewness -1,085,536 Kurtosis -,941 1,038 Tests of Normality Tumor Marker HBV Kolmogorov-Smirnov a Shapiro-Wilk Statistic df Sig. Statistic Df Sig. kadar tumor marker,449 18,000,569 18,000 a. Lilliefors Significance Correction Gambaran Tumor Marker HCV kadar tumor marker Statistic Std. Error 764,67 217,308 L 250,82 o w e 95% Confidence Interval for r B o u n d
U 1278,52 p p e r B o u n d 5% Trimmed 781,70 Median 1210,00 Variance 377783,072 Std. Deviation 614,641 Minimum 13 Maximum 1210 Range 1197 Interquartile Range 1186 Skewness -,644,752 Kurtosis -2,239 1,481 Tests of Normality Tumor Marker HCV Kolmogorov-Smirnov a Shapiro-Wilk Statistic Df Sig. Statistic df Sig. kadar tumor marker,391 8,001,646 8,001 a. Lilliefors Significance Correction Usia kadar gtp Equal variances assumed Equal variances not assumed Equal variances assumed Independent Samples Test nilai laboratorium Levene's Test for t-test for Equality of s Equality of Variances F Sig. T df Sig. (2- Differenc Std. Error 95% Confidence Interval of the Difference tailed) e Differen ce Lower Upper 11,387,003-2,645 24,014-13,375 5,057-23,812-2,938-2,088 8,734,067-13,375 6,405-27,933 1,183 5,285,031 1,854 24,076 135,958 73,327-15,380 287,297
kadar Hb kadar trombosit Equal variances not assumed Equal variances assumed Equal variances not assumed Equal variances assumed Equal variances not assumed 2,246 21,581,035 135,958 60,534 10,278 261,638 1,182,288 -,551 24,586 -,9626 1,7457-4,5656 2,6403 -,483 10,288,639 -,9626 1,9938-5,3884 3,4631 1,552,225,752 24,459 39,194 52,087-68,307 146,696,905 21,235,376 39,194 43,330-50,854 129,243 Uji Bivariat Kadar Laboratorium yang distribusi nya tidak normal kadar ast kadar alt kadar alp kadar albumin kadar pt Mann-Whitney U 40,500 68,000 31,500 69,000 63,500 Wilcoxon W 76,500 104,000 67,500 240,000 234,500 Z -1,751 -,222-2,252 -,167 -,473 Asymp. Sig. (2-tailed),080,824,024,867,636 Exact Sig. [2*(1-tailed Sig.)],080 b,849 b,022 b,892 b,644 b a. Grouping Variable: Kelompok Pasien hepatoma b. Not corrected for ties. Chi-Square Tests kelompok usg (bentuk tumor) Value df Asymp. Sig. (2-sided) Exact Sig. (2- sided) Exact Sig. (1- sided) Point Probability Pearson Chi-Square,431 a 2,806 1,000 Likelihood Ratio,703 2,704 1,000 Fisher's Exact Test,606 1,000 Linear-by-Linear,213 b 1,644,723,498,300 Association N of Valid Cases 21 a. 4 cells (66,7%) have expected count less than 5. The minimum expected count is,29. b. The standardized statistic is,462.
Chi-Square Tests kelompok usg (bentuk tumor) Value df Asymp. Sig. (2- sided) Exact Sig. (2- sided) Exact Sig. (1- sided) Point Probability Pearson Chi-Square,833 a 1,361 1,000,600 Continuity Correction b,000 1 1,000 Likelihood Ratio 1,185 1,276 1,000,600 Fisher's Exact Test 1,000,600 Linear-by-Linear Association,667 c 1,414 1,000,600,600 N of Valid Cases 5 a. 4 cells (100,0%) have expected count less than 5. The minimum expected count is,40. b. Computed only for a 2x2 table Uji Bivariat Tumor Marker kadar tumor marker Mann-Whitney U 65,500 Wilcoxon W 101,500 Z -,442 Asymp. Sig. (2-tailed),659 Exact Sig. [2*(1-tailed Sig.)],724 b a. Grouping Variable: Kelompok Pasien hepatoma b. Not corrected for ties.