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40 6. Dunne JR, et al. Preoperative anemia in colon cancer: assesment of risk factors. Department of Surgery, Veterans Affairs Maryland Health Care System, Baltimore, United State of America. [internet] 2002 [cited on 12 November 2013]. 2002 Jun;68(6):582-7. Available from: Pubmed 7. What is Anemia? [updated May 18, 2012] [cited on 10 November 2013]. Available from: www.nhlbi.nih.gov/health//dci/diseases/anemia/anemia_all.html 8. Sasan Makipour, Bindu Kanapuru, William B. Ershler. Unexplained Anemia in Elderly. Semin Hematol. Author manuscript. [internet] 2008 [cited on 23 November 2013]. Semin Hematol. 2008 October; 45(4): 250 254. Available in PMC 2009 October 1. 2008 9. Vanasse GJ, et al. Anemia in elderly patients: an emerging problem for the 21st century. Hematology Am Soc Hematol Educ Program. [internet] 2010 [cited on 23 November 2013]. 2010;2010:271-5. doi: 10.1182/asheducation-2010.1.271. Available on Pubmed 10. Yu JC, et al. Multicenter cross sectional study of anemia in patients with gastric and colorectal cancer before and after the operation. Zhonghua Wai Ke Za Zhi. [internet] 2011 [cited on 23 November 2013]. 2011 Jan 1;49(1):53-6. Available on : Pubmed 11. Fjørtoft I, et al. Pre-operative anaemia in colon cancer patients became normal after more than a year post-operatively but did not influence oncological outcome in the final analysis. Scand J. Gastroenterol.

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44 Lampiran Lampiran 1. Ethical Clearance

Lampiran 2. Surat Izin Penelitian 45

46 Lampiran 3. Data Rekam Medik No No CM Usia Jenis Kelamin Hb MCH MCV MCHC Lokasi Tinggi Badan Berat Badan IMT 1 C304688 38 L 8,7 23,1 77,7 29,7 Colon Transversum 168 46 16,3 2 A203956 56 P 12,6 28,2 81,4 34,6 Colon Transversum 145 60 28,54 3 C351696 61 L 11 29,9 93 32,1 Colon Transversum 160 57,5 22,46 4 C381057 33 L 13,48 28,36 86,34 32,84 Rectum 168 59 20,9 5 C013636 74 L 14,6 34,4 97,6 35,2 Rectum 165 60 22,04 6 C315729 64 L 13,5 29,3 85,6 34,2 Sigmoid 178 75 23,67 7 C149608 54 L 14 29,7 86,9 34,1 Sigmoid 168 70 24,8 8 C298658 30 L 9,1 20,3 67,6 30 Colon Descenden 166 48 17,42 9 C350118 56 P 12,9 27,9 85,7 32,6 Colon Sigmoid 142 53 26,28 10 C396092 29 L 9,1 25,7 81,9 31,4 Colon Sigmoid 160 38 14,84 11 C367082 33 P 6,49 17,07 56,51 30,2 Colon Transversum 145 38 18,07 12 C325512 60 L 11,9 22,4 70,7 31,7 Rectum 160 50 19,53 13 C243923 55 L 7,1 23,3 73,7 31,6 Rectum 165 60 22,04 14 C296004 42 L 14,3 28,8 88,2 32,6 Colon Ascenden 165 56 20,57 15 B388082 57 P 11,9 28,6 86,3 33,6 Colon ascenden 155 50 20,81 16 C351247 43 L 10,74 24,78 74,36 33,32 Rectum 172 70 23,66 17 C385277 54 P 11,3 27,4 85,8 31,9 Rectum 152 33 14,28 18 C410306 45 P 10,4 27,7 85,4 32,3 Colon Ascenden 142 52 25,79 19 C453558 54 P 6,9 23 73,9 31,2 Colon Ascenden 162 51 19,43 20 C446504 46 L 9,8 29,3 88 33,2 Colon Ascenden 160 45 17,58 21 C453315 39 L 9,8 23,9 75,4 31,8 Rectum 162 53 20,2 22 C450075 79 L 11 30,4 89,7 33,9 Sigmoid 170 60 20,76

47 No No CM Usia Jenis Kelamin Hb MCH MCV MCHC Lokasi Tinggi Badan Berat Badan 23 C242547 29 L 12,2 26,2 82,8 31,7 Colon Sigmoid 165 50 18,37 24 C301620 45 L 16,1 29,5 85,2 34,6 Rectum 163 45 16,94 25 C370798 54 L 7,6 17,1 74,2 23 Colon Ascenden 175 54 17,63 26 C375766 36 L 8,72 22,6 73,2 30,88 Colon Descenden 165 43 15,79 27 C446334 57 L 16,3 30,5 91,4 33,4 Rectum 163 60 22,58 28 C439835 20 L 5,2 20,6 67,3 30,6 Rectum 158 40 16,02 29 C243778 49 P 7,19 27,9 84,5 33,1 Rectum 149 49 22,07 30 C324307 51 P 10,9 30,5 87 35 Rectosigmoid 155 40 16,65 31 C268257 10 L 11,1 28 81,7 34,2 Sigmoid 127 18 11,16 32 C255724 51 L 6,47 24,4 71,3 34,2 Colon Transversum 167 50 17,93 33 C206688 51 L 9,42 25,07 74,01 33,87 Flexura Hepatica 171 60 20,52 34 C240578 57 P 11,7 28,5 83 34,4 Rectum 156 65 26,71 35 C297751 53 L 11,6 24,6 72,2 34 Colon Ascenden 168 55 19,49 36 C309975 49 L 11,64 30,02 86,3 34,78 Anorecti 165 50 18,37 37 C419361 43 P 9,41 24,6 85,6 28,8 Rectum 1/3 distal 148 50 22,83 38 C374807 29 L 14,3 27,4 83 33 Rectosigmoid 155 50 20,81 39 C387745 56 P 9,64 22,1 70,2 31,5 Rectum 163 55 20,7 40 C433059 49 P 12,5 25,2 76,74 32,84 Rectum distal 140 34 17,35 41 C180844 51 L 8,82 26,1 75,3 34,6 Colon Descenden 165 42 15,43 42 610624 55 L 10 23 73,3 31,3 colon Ascenden 168 50 17,72 43 C179171 33 L 9,9 28,2 85,8 32,8 Colon Ascenden 175 60 19,59 44 C182958 46 L 10,4 22,3 66,6 33,5 Colon Ascenden 166 44 15,97 45 C126039 43 L 12,6 28,5 86 33,2 Colon Ascenden 168 43 15,24 IMT

48 No No CM Usia Jenis Kelamin Hb MCH MCV MCHC Lokasi Tinggi Badan Berat Badan 46 C180031 67 L 14,4 30,3 90,1 33,6 Adenoca colon 163 60 22,58 47 C152649 48 P 11,6 28,2 85,3 33,1 Colon Ascenden 155 56 23,31 48 B413607 55 L 5 22,2 72,8 30,6 Colon Transversum 170 50 17,3 49 B247527 46 L 9,1 24,7 81,8 30,3 Colon Ascenden 170 50 17,3 50 C186523 73 P 10 29,8 87,2 34,1 Colon Sigmoid 150 45 20 51 C171536 44 L 8,9 24,2 73,8 32,8 Rectosigmoid 165 57 20,94 52 C438440 46 L 14 32,3 95,1 34 Colon Ascenden 150 60 26,67 53 C372955 67 L 10,7 26 91,8 28,3 Sigmoid 160 67 26,17 54 B369294 70 L 12 26 75,6 34,4 Colon Ascenden 150 50 22,22 IMT

49 Lampiran 4. Hasil Analisis Statistik Uji dengan Chi Square sebelum dilakukan penggabungan sel Case Processing Summary Cases Valid Missing Total N Percent N Percent N Percent Rentang Usia * Status Anemia 54 100,0% 0 0,0% 54 100,0% Rentang Usia * Status Anemia Crosstabulation Status Anemia Total Tidak Anemia Anemia Rentang Usia Total Muda Baya Tua Count 2 10 12 Expected Count 2,9 9,1 12,0 Count 8 26 34 Expected Count 8,2 25,8 34,0 Count 3 5 8 Expected Count 1,9 6,1 8,0 Count 13 41 54 Expected Count 13,0 41,0 54,0 Chi-Square Tests Value df Asymp. Sig. (2- sided) Pearson Chi-Square 1,155 a 2,561 Likelihood Ratio 1,110 2,574 Linear-by-Linear Association 1,050 1,305 N of Valid Cases 54 a. 2 cells (33,3%) have expected count less than 5. The minimum expected count is 1,93.

50 Uji dengan Chi Square setelah dilakukan penggabungan sel Case Processing Summary Cases Valid Missing Total N Percent N Percent N Percent Rentang Usia 2 * Status Anemia 54 100,0% 0 0,0% 54 100,0% Rentang Usia 2 * Status Anemia Crosstabulation Status Anemia Total Tidak Anemia Anemia Rentang Usia 2 Total Muda Baya - Tua Count 2 10 12 Expected Count 2,9 9,1 12,0 Count 11 31 42 Expected Count 10,1 31,9 42,0 Count 13 41 54 Expected Count 13,0 41,0 54,0 Chi-Square Tests Value df Asymp. Sig. (2- sided) Exact Sig. (2- sided) Exact Sig. (1- sided) Pearson Chi-Square,463 a 1,496 Continuity Correction b,089 1,766 Likelihood Ratio,492 1,483 Fisher's Exact Test,708,398 Linear-by-Linear Association,455 1,500 N of Valid Cases 54 a. 1 cells (25,0%) have expected count less than 5. The minimum expected count is 2,89. b. Computed only for a 2x2 table

51 Uji dengan Chi Square Case Processing Summary Cases Valid Missing Total N Percent N Percent N Percent Status Nutrisi * Status Anemia 54 100,0% 0 0,0% 54 100,0% Status Nutrisi * Status Anemia Crosstabulation Status Anemia Total Tidak Anemia Anemia Status Nutrisi Total Status Nutrisi Kurang Status Nutrisi Normal Status Nutrisi Lebih Count 2 20 22 Expected Count 5,3 16,7 22,0 Count 7 18 25 Expected Count 6,0 19,0 25,0 Count 4 3 7 Expected Count 1,7 5,3 7,0 Count 13 41 54 Expected Count 13,0 41,0 54,0 Chi-Square Tests Value df Asymp. Sig. (2- sided) Pearson Chi-Square 7,101 a 2,029 Likelihood Ratio 6,996 2,030 Linear-by-Linear Association 6,808 1,009 N of Valid Cases 54 a. 1 cells (16,7%) have expected count less than 5. The minimum expected count is 1,69.

52 Lampiran 5. Biodata mahasiswa Identitas Nama : Khoirul Fahrizal Rokim NIM : 22010110110113 Tempat Lahir : Karawang Tanggal Lahir : 21 Oktober 1992 Jenis Kelamin : Laki-laki Alamat : Jl. Proklamasi No. 27 Tanjung Mekar, Karawang, Jawa Barat Nomor HP : 085697407070 E-mail : khoirul.fahrizal@ymail.com Riwayat Pendidikan Formal 1. SD : SD Negeri Karang Pawitan 02 Karawang Lulus tahun : 2004 2. SMP : SMP Negeri 1 Karawang Lulus tahun : 2007 3. SMA : SMA Negeri 1 Karawang Lulus tahun : 2010 4. S1 : Pendidikan Dokter Fakultas Kedokteran Universitas Diponegoro Masuk tahun : 2010 Keanggotaan Organisasi 1. BEM Fakultas Kedokteran KM Undip Tahun 2011-2012